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Prof. Vladimir Khavinson
Peptide bioregulators are the future of medicine

Patents

Patent №
Title
Authors
Country, year of issue
1
IL 194344
Pharmaceutical composition revealing a stress protecting effect comprising the peptide H-GLU-ASP-GLY-OH.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Israel, 22.07.2016
2
EP 2667887
Pharmaceutical composition comprising the peptide Glu-Asp-Gly and use for treating. Helicobacter pylori induced gastroduodenal diseases.
Khavinson V.Kh. Kvetnoi I.M. Polyakova V.O. Ryzhak G.A. Kozlov L.V.
European patent, 16.12.2015
3
ЕА 021849
Therapeutic application of Peptide Pharmaceutical Composition for medical treatment of gastroduodenal disorders, caused by Helicobacter pylori.
Khavinson V.Kh. Kvetnoi I.М. Polyakova V.О. Ryzhak G.А. Kozlov L.V.
Eurasia, 30.09.2015
4
IL 194499
Peptide glutamyl-aspartyl-proline, pharmaceutical compositions comprising the peptide and uses of the peptide.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Israel, 31.01.2015
5
IL 194500
Peptide substance enhancing capillaries resistance, pharmaceutical composition on its base and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Israel, 01.05.2014
6
KR 10-1382947
Peptide substance revealing an immunogeroprotective effect, pharmaceutical composition on its base and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
South Korea, 01.04.2014
7
UA 104981
Пептидна фармацевтична композицiя, засiб на її основi для лiкування гастродуоденальних захворювань, якi викликаються Helicobacter pylori, i спосiб його використання. (Peptide pharmaceutical composition, means for treatment of Helicobacter pylori induced gastroduodenal diseases on the basis thereof, and a method of use thereof.)
Khavinson V.Kh. Kvetnoi I.M. Polyakova V.O. Ryzhak G.A. Kozlov L.V.
Ukraine, 25.03.2014
8
US 8,524,674
Method of improving the conditioned reflex habit, the muscle tonus, or the motion coordination of a patient after suffering trauma to the brain cortex.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
USA 03.09.2013
9
KR 10-1289220
Peptide substance stimulating regeneration of central nervous system neurons, pharmaceutical composition on its base, and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
South Korea, 17.07.2013
10
IL 194346
Tripeptide having a stimulating effect on the regeneration of neurons and pharmaceutical composition it.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Israel, 01.04.2013
11
CA 2,335,362
Use of a dipeptide for stimulating repair processes.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Sery S.V.
Canada, 20.11.2012
12
KR 10-1106609
Tetrapeptide regulating blood glucose level in diabetes mellitus.
Khavinson V.Kh. Malinin V.V. Grigoriev E.I. Ryzhak G.A.
South Korea, 10.01.2012
13
US 8,071,556
Peptide substanse revealing a stress protective effect, pharmaceutical composition on its base and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
USA, 06.12.2011
14
CA 2,547,873
Tetrapeptide regulating blood glucose level in diabetes mellitus.
Khavinson V.Kh. Malinin V.V. Grigoriev E.I. Ryzhak G.A.
Canada, 22.11.2011
15
US 8,057,810
Peptide substance revealing an immunogeroprotective effect, pharmaceutical composition on its base and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
USA, 15.11.2011
16
UA 62779
Спосiб лiкування первинної вiдкритокутової глаукоми. (Method of treatment of the primary open-angle glaucoma.)
Panchenko M.V. Khavinson V.Kh. Ryzhak G.A. Panchenko O.M. Samofalova M.M. Alekseenko K.A. Yakubovich N.V.
Ukraine, 12.09.2011
17
EP 2032595
Peptide substance revealing an immunogeroprotective effect, pharmaceutical composition on its base and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
European patent, 22.06.2011
18
IN 247551
Tetrapeptide lisyl-glutamyl-aspartyl-tryptophane amide.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
India, 19.04.2011
19
JP 4668497
Tetrapeptide stimulating functional activity of neurons, pharmacological agent based thereon and method of use thereof.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Grigoriev E.I.
Japan, 13.04.2011
20
CA 2,425,445
Tetrapeptide stimulating functional activity of hepatocytes, pharmacological substance on its basis and the method of its application.
Khavinson V.Kh.
Canada, 18.01.2011
21
US 7,851,449
Peptide, pharmaceutical composition, and a method of treating microcirculation disorders.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
USA, 14.12.2010
22
UA 92387
Пептид, що має стреспротекторну дiю, фармацевтична композицiя на його основi i спосiб її застосування.
(Peptide substance revealing a stress protective effect, pharmaceutical composition on its base and the method of its application.)
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Ukraine, 25.10.2010
23
AU 2004296269
Tetrapeptide regulating blood glucose level in diabetes mellitus.
Grigoriev E.I. Khavinson V.Kh. Ryzhak G.A. Malinin V.V.
Australia, 16.09.2010
24
UA 91137
Пептид, що пiдвищує резистентнiсть капiлярiв, фармацевтична композицiя на його основi i спосiб її застосування.
(Peptide substance enhancing capillaries resistance, pharmaceutical composition on its base and the method of its application.)
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Ukraine, 25.06.2010
25
UA 91136
Пептид, що стимулює регенерацiю нейронiв центральної нервової системи, фармацевтична композицiя на його основi i спосiб її застосування.
(Peptide substance stimulating regeneration of central nervous system neurons, pharmaceutical composition on its base, and the method of its application.)
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Ukraine, 25.06.2010
26
UA 91135
Пептид, що має iмуногеропротекторну дiю, фармацевтична композицiя на його основi i спосiб її застосування. (Peptide substance revealing an immunogeroprotective effect, pharmaceutical composition on its base and the method of its application.)
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Ukraine, 25.06.2010
27
JP 4489946
Use of a dipeptide for stimulating repair processes.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Sery S.V.
Japan, 09.04.2010
28
US 7,662,789
Peptide substance restoring myocardium function.
Khavinson V.Kh. Ryzhak G.A. Grigoriev E.I. Ryadnova I.Yu.
USA, 16.02.2010
29
ЕР 1697401
Tetrapeptide regulating blood glucose level in diabetes mellitus.
Khavinson V.Kh. Malinin V.V. Grigoriev E.I. Ryzhak G.A.
European patent, 06.01.2010
30
US 7,625,870
Peptide substance restoring respiratory organs function.
Khavinson V.Kh. Ryzhak G.A. Grigoriev E.I. Ryadnova I.Yu.
USA, 01.12.2009
31
ЕР 2024387
Peptide substance enhancing capillaries resistance, pharmaceutical composition on its base and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
European patent, 21.10.2009
32
ЕР 2024388
Peptide substance stimulating regeneration of central nervous system neurons, pharmaceutical composition on its base, and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
European patent, 14.10.2009
33
US 7,491,703
Tetrapeptide regulating blood glucose level in diabetes mellitus.
Khavinson V.Kh. Malinin V.V. Grigoriev E.I.v Ryzhak G.A.
USA, 17.02.2009
34
UA 85204
Тетрапептид, що регулює рiвень глюкози в кровi при цукровому дiабетi. (Tetrapeptide regulating glucose level in case of diabetes mellitus)
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Ukraine, 12.01.2009
35
ЕА 011092
Peptide revealing stress protective effect, pharmacological substance based thereon and method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Eurasia, 30.12.2008
36
ЕА 010739
Pharmaceutical substance normalizing brain functions and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
37
ЕА 010738
Pharmaceutical substance normalizing thyroid gland functions and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
38
ЕА 010737
Pharmaceutical substance revealing geroprotective activity and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
39
ЕА 010736
Pharmaceutical substance normalizing female reproductive function and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
40
ЕА 010735
Pharmaceutical substance normalizing male reproductive function and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
41
ЕА 010734
Pharmaceutical substance normalizing blood vessels functions and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
42
ЕА 010724
Pharmaceutical substance normalizing cartilaginous tissue functions and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
43
ЕА 010723
Pharmaceutical substance normalizing kidneys functions and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
44
ЕА 010722
Pharmaceutical substance normalizing urinary bladder tonus and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
45
ЕА 010720
Method for obtaining the substance revealing tissue specific activity for supporting therapy, pharmacological substance produced thereby.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
46
ЕА 010575
Peptide revealing immuno geroprotective effect, pharmacological substance based thereon and method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
47
ЕА 010574
Peptide normalizing osseous and cartilaginous tissue metabolism, pharmacological substance based thereon and method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
48
ЕА 010573
Gepatoprotective substance and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
49
ЕА 010158
Peptide enhancing capillary resistancy, pharmacological substance based thereon and method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Eurasia, 30.06.2008
50
ЕА 010157
Peptide stimulating neurones regeneration, pharmacological substance based thereon and method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Eurasia, 30.06.2008
51
ЕА 010156
Peptide stimulating liver tissue regeneration, pharmacological substance based thereon and method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Eurasia, 30.06.2008
52
ЕР 1758923
Peptide substance restoring myocardium function.
Khavinson V.Kh. Ryzhak G.A. Grigoriev E.I. Ryadnova I.Yu.
European patent, 13.02.2008
53
ЕР 1758922
Peptide substance restoring function of respiratory organs.
Khavinson V.Kh. Ryzhak G.A. Grigoriev E.I. Ryadnova I.Yu.
European patent, 13.02.2008
54
IL 140412
L-LYS-L-GLU dipeptides for pharmaceutical preparations.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Sery S.V.
Israel, 17.09.2007
55
IL 146432
Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.
Khavinson V.Kh.
Israel, 04.09.2007
56
ЕА 008541
Tetrapeptide regulating glucose level in case of diabetes mellitus.
Khavinson V.Kh. Malinin V.V. Grigoriev E.I. Ryzhak G.A.
Eurasia, 29.06.2007
57
LT 5421
Tetrapeptidas, reguliuojantis kraujo gliukozлs lygi, sergant cukriniu diabetu.
(Tetrapeptide regulating glucose level in case of diabetes mellitus)
Khavinson V.Kh. Malinin V.V. Grigoriev E.I. Ryzhak G.A.
Lithuania, 25.05.2007
58
СА 2,373,128
Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.
Khavinson V.Kh.
Canada, 13.03.2007
59
LV 13462
Cukuralоmeni asinоs regulзjoрs tetrapeptоds cukurslimоbas вrstзрanai. (Tetrapeptide regulating glucose level in case of diabetes mellitus)
Khavinson V.Kh. Malinin V.V. Grigoriev E.I. Ryzhak G.A.
Latvia, 20.02.2007
60
US 7,189,701
Tetrapeptide stimulating functional activity of neurons, pharmacological agent based thereon and method of use thereof.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Grigoriev E.I.
USA, 13.03.2007
62
US 7,101,854
Tetrapeptide stimulating the functional activity of hepatocytes, pharmacological substance on its basis and the method of its application.
Khavinson V.Kh.
USA, 05.09.2006
63
AU 784578
Tetrapeptide stimulating functional activity of neurones, pharmacological agent based thereon and method of use thereof.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Grigoriev E.I.
Australia, 17.08.2006
64
ЕР 1179008
Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.
Khavinson V.Kh.
European patent, 22.03.2006
65
AU 776693
Use of a dipeptide for stimulating repair processes.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Sery S.V.
Australia, 06.01.2005
66
DK 175381
Farmaceutisk pr?parat til behandling af immundefekttilstande.
(Pharmaceutical preparation for treating immunodeficiency conditions)
Yakovlev G.M. Morozov V.G. Khavinson V.Kh. Deigin V.I. Korotkov A.M.
Danmark, 20.09.2004
67
AU 769847
Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.
Khavinson V.Kh.
Australia, 20.05.2004
68
ЕР 1353939
Tetrapeptide regulating prostate functions and its compositions and uses.
Khavinson V.Kh. Malinin V.V. Grigoriev E.I.
European patent, 25.08.2004
69
ЕР 1325026
Tetrapeptide stimulating functional activity of hepatocytes and its therapeutical use.
Khavinson V.Kh.
European patent, 18.08.2004
70
US № 6,777,195
Phharmaceutical dipeptide compositions and method of use thereof: immunostimulants.
Kozhemyakin A.L. Sinackevich N.V. Seryi S.V. Rakhilov A.M. Morozov V.G. Khavinson V.Kh.
USA, 17.08.2004
71
US 6,727,227
Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.
Khavinson V.Kh.
USA, 27.04.2004
72
US 6,642,201
Use of a dipeptide for stimulating repair processes.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Sery S.V.
USA, 04.11.2003
73
ЕР 1089753
Use of a dipeptide for stimulating repair processes.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Sery S.V.
European patent, 23.07.2003
74
EP 1224212
Tetrapeptide stimulating functional activity of neurones, pharmacological agent based thereon and method of use thereof.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Grigoriev E.I.
European patent, 09.07.2003
75
СH 692477
Zusammensetzung zur Stimulation von Wiederherstellungsvorgдngen, enthaltend L-Lysil-L-Glutaminsдure.
(Application of dipeptide L-Lys-L-Glu for stimulation of reparative processes)
Khavinson V.Kh. Morozov V.G. Malinin V.V. Sery S.V.
Switzerland and Liechtenstein, 15.07.2002
76
US 6,368,788
Method of treating complications in immunodepressed states resulting from HIV infection.
Kozhemyakin A.L. Sinackevich N.V. Seryi S.V. Rakhilov A.M. Morozov V.G. Khavinson V.Kh.
USA, 09.04.2002
77
US 6,346,514
Pharmaceutical lysine-containing polypeptide compositions and method of use thereof.
Green L.R. Sinackevich N.V. Ivanov V.T. Mikhalyova I.I. Vaskovsky B.V. Mikhaltsov A.N. Khavinson V.Kh. Morozov V.G.
USA, 12.02.2002
78
US 6,139,862
Pharmaceutical dipeptide compositions and methods of use thereof.
Khavinson V.Kh. Sery S.V. Morozov V.G.
USA, 31.10.200
79
US 6,136,788
Pharmaceutical preparation for the therapy of immune deficiency conditions.
Morozov V.G. Khavinson V.Kh
USA, 24.10.2000
80
US 6,100,380
Immunomodulating peptides and methods of use.
Green L.R. Sinackevich N.V. Ivanov V.T. Mikhalyova I.I. Vaskovsky B.V. Mikhaltsov A.N. Morozov V.G. Khavinson V.Kh.
USA, 08.08.2000
81
US 6,066,622
Immunomodulating peptides and methods of use.
Green L.R. Sinackevich N.V. Ivanov V.T. Mikhalyova I.I. Vaskovsky B.V. Mikhaltsov A.N. Khavinson V.Kh. Morozov V.G.
USA, 23.05.2000
82
US 5,814,611
Pharmaceutical for the therapy of immune deficiency conditions.
Morozov V.G. Khavinson V.Kh.
USA, 29.09.1998
83
US 5,811,399
Pharmaceutical dipeptide compositions and methods of use thereof: immunodepressants.
Khavinson V.Kh. Morozov V.G.
USA, 22.09.1998
84
US 5,807,830
Method for treatment of purulent inflammatory diseases.
Morozov V.G. Khavinson V.Kh.
USA, 15.09.1998
85
US 5,789,384
Pharmaceutical dipeptide compositions and methods of use thereof.
Khavinson V.Kh. Sery S.V. Morozov V.G.
USA, 04.08.1998
86
US 5,770,576
Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity.
Morozov V.G. Khavinson V.Kh.
USA, 23.06.1998
87
US 5,767,087
Pharmaceutical preparation for the therapy of immune deficiency conditions.
Morozov V.G. Khavinson V.Kh.
USA, 16.06.1998
88
US 5,728,680
Methods for normalizing numbers of lymphocytes.
Morozov V.G. Khavinson V.Kh.
USA, 17.03.1998
89
US 5,538,951
Pharmaceutical preparation for the therapy of immune deficiency conditions.
Morozov V.G. Khavinson V.Kh.
USA, 23.07.1996
90
JP 2511159
Pharmaceutical preparation for treating immunodeficiency conditions.
Yakovlev G.M. Morozov V.G. Khavinson V.Kh. Deigin V.I. Korotkov A.M.
Japan, 26.06.1996
91
UA 7130
Iмуностимулюючий засiб «Тiмоген». (Immunostimulating substance “Timogen”)
Yakovlev G.M. Morozov V.G. Khavinson V.Kh. Deigin V.I. Korotkov A.M.
Ukraine, 30.06.1995
92
LT 2498
"TIMOGEN".(Immunostimulating substance “Timogen”)
Deigin V. KorotkovA. Khavinson V. Yakovlev G.
Lithuania, 27.04.1994
93
LV 5407
Imьnstimulejoљs lidzeklis “TIMOGEN”.(Immunostimulating substance “Timogen”)
Yakovlev G. Morozov V. Khavinson V. Deigin V. Korotkov A.
Latvia, 10.03.1994
94
CА 1,330,300
Pharmaceutical preparation for therapy of immunodeficit states.
Yakovlev G.M. Morozov V.G. Khavinson V.Kh. Deigin V.I. Korotkov A.M.
Canada, 21.06.1994
95
BY 140
Иммуностимулирующее средство «Тимоген». (Immunostimulating substance “Timogen”)
Yakovlev G.M. Morozov V.G. Khavinson V.Kh. Deigin V.I. Korotkov A.M.
Belarus, 26.10.1993
96
EP 0346501
Arzneimittelzubereitung zur behandlung des immunmangels.
(Pharmaceutical preparation for therapy of immunodeficit states)
Yakovlev G.M. Morozov V.G. Khavinson V.Kh. Deigin V.I. Korotkov A.M.
European patent, 29.07.1992
97
AU 616236
Pharmaceutical preparation for treating immunodeficiency conditions.
Yakovlev G.M. Morozov V.G. Khavinson V.Kh. Deigin V.I. Korotkov A.M.
Australia, 03.03.1992
98
US 5,070,076
Thymus-Gland preparation and method for producing same.
Morozov V.G. Khavinson V.Kh
USA, 03.12.1991
99
JP 1625201
Process for Production of Thymus Gland Preparation.
Morozov V.G. Khavinson V.Kh.
Japan, 18.11.1991
100
Fr 2583982
Produit medicamenteux obtenu a partir du thymus et son procede d'obtention.
(Thymus-gland substance and method for producing the same)
Morozov V.G. Khavinson V.Kh.
France, 24.02.1989
101
DE 3421789
Arzneimittel auf der Basis einer Thymusfraktion und Verfahren zu dessen Herstellung.
(Thymus-gland substance and method for producing the same)
Morozov V.G. Khavinson V.Kh.
Germany, 06.10.1988
102
CH 659586
Arzneimittel aus dem Thymus und Verfahren zu dessen Herstellung.
(Pharmaceutical substance from thymus gland and method for producing the same)
Morozov V.G. Khavinson V.Kh.
Switzerland and Liechtenstein 13.02.1987