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Prof. Vladimir Khavinson
Peptide bioregulators are the future of medicine

Patents

Patent №
Title
Authors
Country, year of issue
1.
US 11,083,770
Medical preparation and method for enhancing tissue oxygenation in case of diabetic foot.
Trofimov A.V. Khavinson V.Kh. Ivko O.M. Trofimova S.V.
USA, 10.08.2021
2.
EP 3 638 281
L-GLU-L-TRP for enhancing tissue oxygenation in case of diabetic foot and use of it.
Trofimov A.V. Khavinson V.Kh. Ivko O.M. Trofimova S.V.
European patent, 03.03.2021
3.
AU 2017439352
Medical preparation for enhancing tissue oxygenation in case of diabetic foot and use of it.
Trofimov A.V. Khavinson V.Kh. Ivko O.M. Trofimova S.V.
Australia, 07.01.2021
4.
IL 194344
Pharmaceutical composition revealing a stress protecting effect comprising the peptide H-GLU-ASP-GLY-OH.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Israel, 22.07.2016
5.
EP 2667887
Pharmaceutical composition comprising the peptide Glu-Asp-Gly and use for treating. Helicobacter pylori induced gastroduodenal diseases.
Khavinson V.Kh. Kvetnoi I.M. Polyakova V.O. Ryzhak G.A. Kozlov L.V.
European patent, 16.12.2015
6.
ЕА 021849
Therapeutic application of Peptide Pharmaceutical Composition for medical treatment of gastroduodenal disorders, caused by Helicobacter pylori.
Khavinson V.Kh. Kvetnoi I.М. Polyakova V.О. Ryzhak G.А. Kozlov L.V.
Eurasia, 30.09.2015
7.
IL 194499
Peptide glutamyl-aspartyl-proline, pharmaceutical compositions comprising the peptide and uses of the peptide.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Israel, 31.01.2015
8.
IL 194500
Peptide substance enhancing capillaries resistance, pharmaceutical composition on its base and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Israel, 01.05.2014
9.
KR 10-1382947
Peptide substance revealing an immunogeroprotective effect, pharmaceutical composition on its base and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
South Korea, 01.04.2014
10.
UA 104981
Пептидна фармацевтична композицiя, засiб на її основi для лiкування гастродуоденальних захворювань, якi викликаються Helicobacter pylori, i спосiб його використання. (Peptide pharmaceutical composition, means for treatment of Helicobacter pylori induced gastroduodenal diseases on the basis thereof, and a method of use thereof.)
Khavinson V.Kh. Kvetnoi I.M. Polyakova V.O. Ryzhak G.A. Kozlov L.V.
Ukraine, 25.03.2014
11.
US 8,524,674
Method of improving the conditioned reflex habit, the muscle tonus, or the motion coordination of a patient after suffering trauma to the brain cortex.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
USA 03.09.2013
12.
KR 10-1289220
Peptide substance stimulating regeneration of central nervous system neurons, pharmaceutical composition on its base, and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
South Korea, 17.07.2013
13.
IL 194346
Tripeptide having a stimulating effect on the regeneration of neurons and pharmaceutical composition it.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Israel, 01.04.2013
14.
CA 2,335,362
Use of a dipeptide for stimulating repair processes.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Sery S.V.
Canada, 20.11.2012
15.
KR 10-1106609
Tetrapeptide regulating blood glucose level in diabetes mellitus.
Khavinson V.Kh. Malinin V.V. Grigoriev E.I. Ryzhak G.A.
South Korea, 10.01.2012
16.
US 8,071,556
Peptide substanse revealing a stress protective effect, pharmaceutical composition on its base and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
USA, 06.12.2011
17.
CA 2,547,873
Tetrapeptide regulating blood glucose level in diabetes mellitus.
Khavinson V.Kh. Malinin V.V. Grigoriev E.I. Ryzhak G.A.
Canada, 22.11.2011
18.
US 8,057,810
Peptide substance revealing an immunogeroprotective effect, pharmaceutical composition on its base and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
USA, 15.11.2011
19.
UA 62779
Спосiб лiкування первинної вiдкритокутової глаукоми. (Method of treatment of the primary open-angle glaucoma.)
Panchenko M.V. Khavinson V.Kh. Ryzhak G.A. Panchenko O.M. Samofalova M.M. Alekseenko K.A. Yakubovich N.V.
Ukraine, 12.09.2011
20.
EP 2032595
Peptide substance revealing an immunogeroprotective effect, pharmaceutical composition on its base and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
European patent, 22.06.2011
21.
IN 247551
Tetrapeptide lisyl-glutamyl-aspartyl-tryptophane amide.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
India, 19.04.2011
22.
JP 4668497
Tetrapeptide stimulating functional activity of neurons, pharmacological agent based thereon and method of use thereof.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Grigoriev E.I.
Japan, 13.04.2011
23.
CA 2,425,445
Tetrapeptide stimulating functional activity of hepatocytes, pharmacological substance on its basis and the method of its application.
Khavinson V.Kh.
Canada, 18.01.2011
24.
US 7,851,449
Peptide, pharmaceutical composition, and a method of treating microcirculation disorders.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
USA, 14.12.2010
25.
UA 92387
Пептид, що має стреспротекторну дiю, фармацевтична композицiя на його основi i спосiб її застосування.
(Peptide substance revealing a stress protective effect, pharmaceutical composition on its base and the method of its application.)
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Ukraine, 25.10.2010
26.
AU 2004296269
Tetrapeptide regulating blood glucose level in diabetes mellitus.
Grigoriev E.I. Khavinson V.Kh. Ryzhak G.A. Malinin V.V.
Australia, 16.09.2010
27.
UA 91137
Пептид, що пiдвищує резистентнiсть капiлярiв, фармацевтична композицiя на його основi i спосiб її застосування.
(Peptide substance enhancing capillaries resistance, pharmaceutical composition on its base and the method of its application.)
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Ukraine, 25.06.2010
28.
UA 91136
Пептид, що стимулює регенерацiю нейронiв центральної нервової системи, фармацевтична композицiя на його основi i спосiб її застосування.
(Peptide substance stimulating regeneration of central nervous system neurons, pharmaceutical composition on its base, and the method of its application.)
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Ukraine, 25.06.2010
29.
UA 91135
Пептид, що має iмуногеропротекторну дiю, фармацевтична композицiя на його основi i спосiб її застосування. (Peptide substance revealing an immunogeroprotective effect, pharmaceutical composition on its base and the method of its application.)
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Ukraine, 25.06.2010
30.
JP 4489946
Use of a dipeptide for stimulating repair processes.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Sery S.V.
Japan, 09.04.2010
31.
US 7,662,789
Peptide substance restoring myocardium function.
Khavinson V.Kh. Ryzhak G.A. Grigoriev E.I. Ryadnova I.Yu.
USA, 16.02.2010
32.
ЕР 1697401
Tetrapeptide regulating blood glucose level in diabetes mellitus.
Khavinson V.Kh. Malinin V.V. Grigoriev E.I. Ryzhak G.A.
European patent, 06.01.2010
33.
US 7,625,870
Peptide substance restoring respiratory organs function.
Khavinson V.Kh. Ryzhak G.A. Grigoriev E.I. Ryadnova I.Yu.
USA, 01.12.2009
34.
ЕР 2024387
Peptide substance enhancing capillaries resistance, pharmaceutical composition on its base and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
European patent, 21.10.2009
35.
ЕР 2024388
Peptide substance stimulating regeneration of central nervous system neurons, pharmaceutical composition on its base, and the method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
European patent, 14.10.2009
36.
US 7,491,703
Tetrapeptide regulating blood glucose level in diabetes mellitus.
Khavinson V.Kh. Malinin V.V. Grigoriev E.I.v Ryzhak G.A.
USA, 17.02.2009
37.
UA 85204
Тетрапептид, що регулює рiвень глюкози в кровi при цукровому дiабетi. (Tetrapeptide regulating glucose level in case of diabetes mellitus)
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Ukraine, 12.01.2009
38.
ЕА 011092
Peptide revealing stress protective effect, pharmacological substance based thereon and method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Eurasia, 30.12.2008
39.
ЕА 010739
Pharmaceutical substance normalizing brain functions and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
40.
ЕА 010738
Pharmaceutical substance normalizing thyroid gland functions and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
41.
ЕА 010737
Pharmaceutical substance revealing geroprotective activity and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
42.
ЕА 010736
Pharmaceutical substance normalizing female reproductive function and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
43.
ЕА 010735
Pharmaceutical substance normalizing male reproductive function and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
44.
ЕА 010734
Pharmaceutical substance normalizing blood vessels functions and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
45.
ЕА 010724
Pharmaceutical substance normalizing cartilaginous tissue functions and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
46.
ЕА 010723
Pharmaceutical substance normalizing kidneys functions and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
47.
ЕА 010722
Pharmaceutical substance normalizing urinary bladder tonus and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
48.
ЕА 010720
Method for obtaining the substance revealing tissue specific activity for supporting therapy, pharmacological substance produced thereby.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
49.
ЕА 010575
Peptide revealing immuno geroprotective effect, pharmacological substance based thereon and method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
50.
ЕА 010574
Peptide normalizing osseous and cartilaginous tissue metabolism, pharmacological substance based thereon and method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
51.
ЕА 010573
Gepatoprotective substance and method for producing the same.
Khavinson V.Kh. Malinin V.V. Ryzhak G.A.
Eurasia, 30.10.2008
52.
ЕА 010158
Peptide enhancing capillary resistancy, pharmacological substance based thereon and method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Eurasia, 30.06.2008
53.
ЕА 010157
Peptide stimulating neurones regeneration, pharmacological substance based thereon and method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Eurasia, 30.06.2008
54.
ЕА 010156
Peptide stimulating liver tissue regeneration, pharmacological substance based thereon and method of its application.
Khavinson V.Kh. Grigoriev E.I. Malinin V.V. Ryzhak G.A.
Eurasia, 30.06.2008
55.
ЕР 1758923
Peptide substance restoring myocardium function.
Khavinson V.Kh. Ryzhak G.A. Grigoriev E.I. Ryadnova I.Yu.
European patent, 13.02.2008
56.
ЕР 1758922
Peptide substance restoring function of respiratory organs.
Khavinson V.Kh. Ryzhak G.A. Grigoriev E.I. Ryadnova I.Yu.
European patent, 13.02.2008
57.
IL 140412
L-LYS-L-GLU dipeptides for pharmaceutical preparations.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Sery S.V.
Israel, 17.09.2007
58.
IL 146432
Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.
Khavinson V.Kh.
Israel, 04.09.2007
59.
ЕА 008541
Tetrapeptide regulating glucose level in case of diabetes mellitus.
Khavinson V.Kh. Malinin V.V. Grigoriev E.I. Ryzhak G.A.
Eurasia, 29.06.2007
60.
LT 5421
Tetrapeptidas, reguliuojantis kraujo gliukozлs lygi, sergant cukriniu diabetu.
(Tetrapeptide regulating glucose level in case of diabetes mellitus)
Khavinson V.Kh. Malinin V.V. Grigoriev E.I. Ryzhak G.A.
Lithuania, 25.05.2007
61.
СА 2,373,128
Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.
Khavinson V.Kh.
Canada, 13.03.2007
62.
LV 13462
Cukuralоmeni asinоs regulзjoрs tetrapeptоds cukurslimоbas вrstзрanai. (Tetrapeptide regulating glucose level in case of diabetes mellitus)
Khavinson V.Kh. Malinin V.V. Grigoriev E.I. Ryzhak G.A.
Latvia, 20.02.2007
63.
US 7,189,701
Tetrapeptide stimulating functional activity of neurons, pharmacological agent based thereon and method of use thereof.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Grigoriev E.I.
USA, 13.03.2007
65.
US 7,101,854
Tetrapeptide stimulating the functional activity of hepatocytes, pharmacological substance on its basis and the method of its application.
Khavinson V.Kh.
USA, 05.09.2006
66.
AU 784578
Tetrapeptide stimulating functional activity of neurones, pharmacological agent based thereon and method of use thereof.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Grigoriev E.I.
Australia, 17.08.2006
67.
ЕР 1179008
Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.
Khavinson V.Kh.
European patent, 22.03.2006
68.
AU 776693
Use of a dipeptide for stimulating repair processes.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Sery S.V.
Australia, 06.01.2005
69.
DK 175381
Farmaceutisk pr?parat til behandling af immundefekttilstande.
(Pharmaceutical preparation for treating immunodeficiency conditions)
Yakovlev G.M. Morozov V.G. Khavinson V.Kh. Deigin V.I. Korotkov A.M.
Danmark, 20.09.2004
70.
AU 769847
Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.
Khavinson V.Kh.
Australia, 20.05.2004
71.
ЕР 1353939
Tetrapeptide regulating prostate functions and its compositions and uses.
Khavinson V.Kh. Malinin V.V. Grigoriev E.I.
European patent, 25.08.2004
72.
ЕР 1325026
Tetrapeptide stimulating functional activity of hepatocytes and its therapeutical use.
Khavinson V.Kh.
European patent, 18.08.2004
73.
US № 6,777,195
Phharmaceutical dipeptide compositions and method of use thereof: immunostimulants.
Kozhemyakin A.L. Sinackevich N.V. Seryi S.V. Rakhilov A.M. Morozov V.G. Khavinson V.Kh.
USA, 17.08.2004
74.
US 6,727,227
Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.
Khavinson V.Kh.
USA, 27.04.2004
75.
US 6,642,201
Use of a dipeptide for stimulating repair processes.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Sery S.V.
USA, 04.11.2003
76.
ЕР 1089753
Use of a dipeptide for stimulating repair processes.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Sery S.V.
European patent, 23.07.2003
77.
EP 1224212
Tetrapeptide stimulating functional activity of neurones, pharmacological agent based thereon and method of use thereof.
Khavinson V.Kh. Morozov V.G. Malinin V.V. Grigoriev E.I.
European patent, 09.07.2003
78.
СH 692477
Zusammensetzung zur Stimulation von Wiederherstellungsvorgдngen, enthaltend L-Lysil-L-Glutaminsдure.
(Application of dipeptide L-Lys-L-Glu for stimulation of reparative processes)
Khavinson V.Kh. Morozov V.G. Malinin V.V. Sery S.V.
Switzerland and Liechtenstein, 15.07.2002
79.
US 6,368,788
Method of treating complications in immunodepressed states resulting from HIV infection.
Kozhemyakin A.L. Sinackevich N.V. Seryi S.V. Rakhilov A.M. Morozov V.G. Khavinson V.Kh.
USA, 09.04.2002
80.
US 6,346,514
Pharmaceutical lysine-containing polypeptide compositions and method of use thereof.
Green L.R. Sinackevich N.V. Ivanov V.T. Mikhalyova I.I. Vaskovsky B.V. Mikhaltsov A.N. Khavinson V.Kh. Morozov V.G.
USA, 12.02.2002
81.
US 6,139,862
Pharmaceutical dipeptide compositions and methods of use thereof.
Khavinson V.Kh. Sery S.V. Morozov V.G.
USA, 31.10.200
82.
US 6,136,788
Pharmaceutical preparation for the therapy of immune deficiency conditions.
Morozov V.G. Khavinson V.Kh
USA, 24.10.2000
83.
US 6,100,380
Immunomodulating peptides and methods of use.
Green L.R. Sinackevich N.V. Ivanov V.T. Mikhalyova I.I. Vaskovsky B.V. Mikhaltsov A.N. Morozov V.G. Khavinson V.Kh.
USA, 08.08.2000
84.
US 6,066,622
Immunomodulating peptides and methods of use.
Green L.R. Sinackevich N.V. Ivanov V.T. Mikhalyova I.I. Vaskovsky B.V. Mikhaltsov A.N. Khavinson V.Kh. Morozov V.G.
USA, 23.05.2000
85.
US 5,814,611
Pharmaceutical for the therapy of immune deficiency conditions.
Morozov V.G. Khavinson V.Kh.
USA, 29.09.1998
86.
US 5,811,399
Pharmaceutical dipeptide compositions and methods of use thereof: immunodepressants.
Khavinson V.Kh. Morozov V.G.
USA, 22.09.1998
87.
US 5,807,830
Method for treatment of purulent inflammatory diseases.
Morozov V.G. Khavinson V.Kh.
USA, 15.09.1998
88.
US 5,789,384
Pharmaceutical dipeptide compositions and methods of use thereof.
Khavinson V.Kh. Sery S.V. Morozov V.G.
USA, 04.08.1998
89.
US 5,770,576
Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity.
Morozov V.G. Khavinson V.Kh.
USA, 23.06.1998
90.
US 5,767,087
Pharmaceutical preparation for the therapy of immune deficiency conditions.
Morozov V.G. Khavinson V.Kh.
USA, 16.06.1998
91.
US 5,728,680
Methods for normalizing numbers of lymphocytes.
Morozov V.G. Khavinson V.Kh.
USA, 17.03.1998
92.
US 5,538,951
Pharmaceutical preparation for the therapy of immune deficiency conditions.
Morozov V.G. Khavinson V.Kh.
USA, 23.07.1996
93.
JP 2511159
Pharmaceutical preparation for treating immunodeficiency conditions.
Yakovlev G.M. Morozov V.G. Khavinson V.Kh. Deigin V.I. Korotkov A.M.
Japan, 26.06.1996
94.
UA 7130
Iмуностимулюючий засiб «Тiмоген». (Immunostimulating substance “Timogen”)
Yakovlev G.M. Morozov V.G. Khavinson V.Kh. Deigin V.I. Korotkov A.M.
Ukraine, 30.06.1995
95.
LT 2498
"TIMOGEN".(Immunostimulating substance “Timogen”)
Deigin V. KorotkovA. Khavinson V. Yakovlev G.
Lithuania, 27.04.1994
96.
LV 5407
Imьnstimulejoљs lidzeklis “TIMOGEN”.(Immunostimulating substance “Timogen”)
Yakovlev G. Morozov V. Khavinson V. Deigin V. Korotkov A.
Latvia, 10.03.1994
97.
CА 1,330,300
Pharmaceutical preparation for therapy of immunodeficit states.
Yakovlev G.M. Morozov V.G. Khavinson V.Kh. Deigin V.I. Korotkov A.M.
Canada, 21.06.1994
98.
BY 140
Иммуностимулирующее средство «Тимоген». (Immunostimulating substance “Timogen”)
Yakovlev G.M. Morozov V.G. Khavinson V.Kh. Deigin V.I. Korotkov A.M.
Belarus, 26.10.1993
99.
EP 0346501
Arzneimittelzubereitung zur behandlung des immunmangels.
(Pharmaceutical preparation for therapy of immunodeficit states)
Yakovlev G.M. Morozov V.G. Khavinson V.Kh. Deigin V.I. Korotkov A.M.
European patent, 29.07.1992
100.
AU 616236
Pharmaceutical preparation for treating immunodeficiency conditions.
Yakovlev G.M. Morozov V.G. Khavinson V.Kh. Deigin V.I. Korotkov A.M.
Australia, 03.03.1992
101.
US 5,070,076
Thymus-Gland preparation and method for producing same.
Morozov V.G. Khavinson V.Kh
USA, 03.12.1991
102.
JP 1625201
Process for Production of Thymus Gland Preparation.
Morozov V.G. Khavinson V.Kh.
Japan, 18.11.1991
103.
Fr 2583982
Produit medicamenteux obtenu a partir du thymus et son procede d'obtention.
(Thymus-gland substance and method for producing the same)
Morozov V.G. Khavinson V.Kh.
France, 24.02.1989
104.
DE 3421789
Arzneimittel auf der Basis einer Thymusfraktion und Verfahren zu dessen Herstellung.
(Thymus-gland substance and method for producing the same)
Morozov V.G. Khavinson V.Kh.
Germany, 06.10.1988
105.
CH 659586
Arzneimittel aus dem Thymus und Verfahren zu dessen Herstellung.
(Pharmaceutical substance from thymus gland and method for producing the same)
Morozov V.G. Khavinson V.Kh.
Switzerland and Liechtenstein, 13.02.1987